Extracellular matrix Assay techniques

Hyaluronidase is involved in bacterial and fungal infections because of virulence factors evoked by tissue degradation and mediates host-pathogen interactions [47]. Since hyaluronic acid (HA) is a major component of the extracellular matrix involved in joint lubrication, a sensitive hyaluronidase assay is important. Current hyaluronidase assays rely on turbidimetric techniques that require high levels of the enz3Tne and are relatively inaccurate [47]. HA was previously shown to bind cyanines [48,49[. The detection scheme designed for CMA, CMC, and amylase enzyme described earlier was also applicable to HA and hyaluronidase activity [19]. Scaffold Destruction ... 

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