Exogenous Long Chain Triglycerides

To the liver has been attributed a significant role in initial removal of chylomicrons from plasma (Nestel et al. 1962), and evidence has been presented suggesting uptake of fat particles as units rather than fragments (Havel and Fredrickson 1956). Felts (1965), from careful studies with fresh chylomicrons, has recently questioned the quantitative importance of this process. 

Uptake of most of the chylomicron glycerides by adipose tissue is preceded by hydrolysis (Rodbell and Scow 1965), which is mediated, according to present concepts, by the enzyme(s) lipoprotein lipase located within the capillary wall (recently reviewed by Engelberg 1960). 

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