Turkey excreta

In this study, three experimental tanks were employed Tank A containing excreta from a turkey treated with carbon-lA robeni-dine Tank B containing excreta fortified with carbon-1A DDT which was used as a positive control and Tank C containing untreated excreta which was used as a control. 

To obtain excreta for this study, a turkey was fed 250 grams of a basal diet containing 66 ppm robenidine hydrochloride for ten days. On the eleventh day, the turkey was dosed with 17 mg or 316.37 pCi of carbon-lA robenidine in a capsule. 

The total radioactivity applied to the soil as carbon-lA robenidine residues in excreta was 167.5A microcuries. For Tank B, 100 microcuries of carbon-1A DDT and 9 mg of unlabeled DDT were mixed in a ball mill with 2.5 kg of soil and 52g of control turkey excreta. The amount of DDT added to the soil corresponded to an application rate of approximately 1.5 lbs/acre. For Tank C, control turkey excreta was mixed with the top two inches of soil as previously described. 

Approximately 60% of the carbon-14 robenidine administered to the turkey was recovered in the excreta within 48 hours. 

Figure 3. TLC of the extractable radioactivity from the excreta of turkeys...

Metabolism of maduramicin in various animal species seems to proceed in a manner similar to monensin. Selective 0-demethylation of one or two methoxy groups has been reported as the major biotransformation route in chickens and rats (30), whereas O-demethylation of one or more methoxy groups followed by hydroxylation is the major biotransformation route in turkey excreta (31). Conjugation with glucuronic acid also occurs but it is of minor metabolic importance. 

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