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Excitotoxic index

The excitotoxic index was developed by our group as a composite descriptor of excitatory/inhibitory amino acid neurotransmitter balance as measured by microdialysis in the brain s extracellular space (66,102). This index is defined as ... [Pg.28]

Our group was able to show that 12.5 min of normothermic global ischemia led to significant, 7- to 12-fold increases in the striatal excitotoxic index that persisted for 3 4 h. By contrast, animals with postischemic hypothermia (30°C for 3 h) showed no changes in the excitotoxic index during recirculation (103). [Pg.28]

Globus M. Y., Ginsberg M. D., and Busto R. (1991) Excitotoxic index—a biochemical marker of selective vulnerability. Neurosci. Lett. 127, 39-42. [Pg.35]

Early moderatepostischemic hypothermia attenuates the rise in excitotoxic index in the hippocampus—a possible mechanism for the beneficial effects of postischemic moderate cooBng. J. Cereb. Blood Flow Metab. 11, S10. [Pg.37]

See other pages where Excitotoxic index is mentioned: [Pg.25]    [Pg.28]    [Pg.156]    [Pg.4718]    [Pg.25]    [Pg.28]    [Pg.156]    [Pg.4718]    [Pg.232]    [Pg.153]    [Pg.208]    [Pg.339]    [Pg.154]    [Pg.56]   
See also in sourсe #XX -- [ Pg.25 , Pg.28 ]



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