Excited UCNPs

Since Nd -sensitized UCNPs have the potential to be the next generation of luminophores, NIR nanocarriers based on 808 nm excited UCNPs are also being developed. The major strategies immobilizing the biomolecules onto the 808 nm excited UCNPs are similar to those for the 980 nm excited UCNPs mentioned above, such as using adsorbed or tethered polymers or... 

Figure 1.2 (a) PL spectra of NaYF4 2% Tm, 20% UCNPs in aqueous dispersion excitation at 975 run. Inset sample of the UCNPs... 

Although great advances have been made by Moghe and his colleagues, 980 nm-excited lanthanide-based NIR nanomaterials, both UCNPs and DCNPs, suffer from the same problem the water in biological structures... 

Multifunctional UCNPs coated with a PEG-phospholipid layer for aqueous solubility were reported by Chen et al. Core-shell NaYF4 Yb,Tm-NaYF4 Yb,Er UCNPs (-31 nm) codoped with Er and Tm were chosen due to their multiple emissions at 539, 654, and 802 nm. Under 980 nm excitation, the NIR-to-vis-ible UCL was used to excite the PS Ce6 physically adsorbed on the hydrophobic layer on the nanoparticles and therefore, to produce 62. The NIR-to-NIR UCL was used for NIR imaging. The loading efficiency of Ce6 on the UCNP was estimated to be 23% (wAv) and no leakage of the PS was observed when the particles were kept in PB for up to 7 days. The production of O2 by the... 

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