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Evolution Screening Hypothesis

The Screening Hypothesis seeks to explain the evolution of NPs when the chances of any one NP benefiting the producer are indeed very low. This simple hypothesis predicts that certain metabolic traits which favour the generation and retention of NP diversity will be retained during the evolution of NP metabolism. The most important of these predicted metabolic traits is the ability of enzymes making NPs to either accept... [Pg.91]

The implications of the Law of Mass Action to the evolution of NPs—the Screening Hypothesis... [Pg.112]

The evolutionary constraint that lies at the heart of the Screening Hypothesis (that any molecule has a low probability of possessing potent biomolecular activity—see Chapter 5 for detailed arguments) must have influenced the evolution of inducibility. The reasoning behind this statement requires a recap of some principles. [Pg.186]


See other pages where Evolution Screening Hypothesis is mentioned: [Pg.102]    [Pg.121]    [Pg.216]    [Pg.309]    [Pg.393]    [Pg.79]    [Pg.70]    [Pg.825]    [Pg.346]    [Pg.464]    [Pg.460]    [Pg.1]   


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Screening Hypothesis

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