Eucalyptol determination

Sfi f-Tfst F.4A Use the molar composition of eucalyptol calculated in Self-Test F.3B to determine its empirical formula. 

Eucalyptus leaves are the food source for panda bears. Eucalyptol is an oil found in these leaves. Analysis of eucalyptol indicates it has a molar mass of 154 g/mol and contains 77.87% C, 11.76% H, and 10.37% O. Determine the molecular formula of eucalyptol. 

A diet containing Brussel sprouts, cabbage, and cauliflower was found to stimulate CYP450 activity in rat intestine (39). It was subsequently determined that indole derivatives (indole-3-carbinol) were responsible for the enzyme induction. Other examples of chemicals found naturally in foods that enhance metabolism in animals are flavones, safrole, eucalyptol, xanthines, p-ionone, and organic peroxides. Volatile oils in soft woods (e.g., cedar) have been shown to be enzyme inducers. 

Terpene oxides, epoxides or peroxides are encountered more often than is usually believed during TLC of essential oils [248]. Eucalyptol (1,8-cineole) and ascaridole, which is easily accessible by photochemical treatment of a-terpinene, are the best known. These compound types play a special part in the determination of the value of individual oils. 

Commercially, preparations are encountered with anhydrous ephedrine, in an oily base, usually containing eucalyptol, camphor and menthol. The ephedrine in such preparations can readily be determined by mixing a suitable volume with glacial acetic acid and toluene and carrying out a direct non-aqueous titration with perchloric acid in glacial acetic acid. 

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