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Ethyl thiolacetate

The reference reaction is the formation of ethyl thiolacetate from ethanethiol and acetic acid (Gerstein and Jencks, 1964) c Storm and Koshland, 1972b... [Pg.253]

Phenylacetonitrile Ethyl thiolacetate Unidentified ketone (mol mass 138)... [Pg.268]

Thiol Substitution Reactions. Vital to the usefulness of 2-(trimethylsilyl)ethanethiol is that it behaves as a typical thiol. Base mediated reactions that proceed as expected include alkylation and nucleophilic ring openings. Moreover, addition-eliminations on unsaturated systems, Michael additions, and c -additions to triple bonds (eq 2) are all routine. To access 2-(trimethylsilyl)ethyl thioethers, a useful procedure is hydrolysis of 2-(trimethylsilyl)ethyl thiolacetate and alkylation of the thiolate in a single pot. ... [Pg.619]

Thiol esters can be reduced to sulfides or aldehydes. Alone generated from lithium aluminum hydride and boron trifluoride etherate [1099] or aluminum chloride [1100] in ether reduced the carbonyl group to methylene and gave yi-9y /o yields of sulfides. Phenyl thiolbenzoate failed to give the sulfide, and phenyl thiolacetate gave only an 8% yield of ethyl phenyl sulfide [1100]. [Pg.163]

Sulfanylalkanoyl amino acids and peptides are prepared by reaction of the (acetyl-sulfanyl)- or (benzoylsulfanyl)alkanoic acids or acid chlorides with a-amino esters or peptide esters, followed by deprotection of the sulfanyl and carboxy groups. 8 101114 16 27 29 For example, the 3-(acetylsulfanyl)alkanoic acids 7 are prepared from the condensation of ethyl (diethoxyphosphoryl) acetate 5 with various aldehydes according to the Horner-Emmons reaction, providing the a, 3-unsaturated ethyl esters 6 (a mixture of Z- and E-isomers, 50 50), followed by saponification of the ethyl esters and Michael addition of thiolacetic acid. The 3-(acetylsulfanyl)alkanoic acids 7 can be coupled with a-amino esters or peptide esters and subsequent hydrolysis of the 3-(acetylsulfanyl) derivatives provides the desired products 8 (Scheme 2). 14 ... [Pg.306]

Ethyl 8-chloroformylvalerate Thiolacetic acid Ethyl-6,8-dibromooctanoate Iodoform... [Pg.3202]

The enzyme is specific for thiol esters of the type of S-acetyl and S-butyryl glutathione. Besides the three thiol esters already discussed, ethyl thiol-acetate, butyl thiolacetate, acetyl thioglycolic acid, acetyl mercapto propionic acid, S-acetyl-2 mercaptoethanol, acetyl thiomalic, acetyl coenzyme A, and butjryl coenzyme A were inactive with the purified enzyme. Crude extracts of liver attacked butyl thiolacetate and acetyl coenzyme A slowly. [Pg.206]

Related Reagents. Benzyl thiol f-butanethiol potassium ethyl xanthate 2-cyanoethanethiol thiolacetic acid. [Pg.621]

See other pages where Ethyl thiolacetate is mentioned: [Pg.596]    [Pg.865]    [Pg.196]    [Pg.210]    [Pg.85]    [Pg.419]    [Pg.524]    [Pg.1040]    [Pg.472]    [Pg.133]    [Pg.472]    [Pg.478]    [Pg.1019]    [Pg.1069]    [Pg.1168]    [Pg.596]    [Pg.865]    [Pg.196]    [Pg.210]    [Pg.85]    [Pg.419]    [Pg.524]    [Pg.1040]    [Pg.472]    [Pg.133]    [Pg.472]    [Pg.478]    [Pg.1019]    [Pg.1069]    [Pg.1168]    [Pg.3203]    [Pg.559]    [Pg.8]    [Pg.42]    [Pg.67]    [Pg.69]    [Pg.74]    [Pg.631]    [Pg.559]    [Pg.258]    [Pg.301]    [Pg.8]    [Pg.42]    [Pg.67]    [Pg.69]    [Pg.74]    [Pg.156]    [Pg.181]    [Pg.93]    [Pg.17]    [Pg.114]    [Pg.205]    [Pg.44]    [Pg.618]    [Pg.287]   
See also in sourсe #XX -- [ Pg.206 ]



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2- Thiolacetate

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