Ethyl carbonate Ibuprofen

Ethyl a-bromobutyrate Cyclobutyrol Ethyl bromoisobutyrate Methallenestril Ethyl-2-bromo propionate Naproxen Ethyl carbonate Ibuprofen Ethyl chloride Oxeladin... 

Synthesis (Mayer and Testa, 1997 Cleij et al., 1999 Kleemann et al., 1999) a) Treatment of ethyl 4-isobutylphenylacetate and diethyl carbonate with sodium ethoxide gives diethyl 4-isobutylphenylmalonate, which is methylated using methyl iodide and sodium ethoxide. Saponification followed by decarboxylation of the resulting malonic acid derivative affords ibuprofen. 

---