Ethers of D-mannose

Aspinall, G. 0., The Methyl Ethers of Hexuronie Acids, IX, 131-148 Aspinall, G. 0., The Methyl Ethers of D-Mannose, VIII, 217-230... 

The importance of the methyl ethers of D-mannose lies largely in their occurrence in structural studies in the polysaccharide field. Since previous articles in this series14 have discussed the basic principles involved in the preparation and elucidation of the structure of partially methylated aldoses, it is not intended to give unnecessary details in cases where general procedures are already familiar. 

In this manner 6-methyl-D-glucopyranose (XXIX) and some of its derivatives were synthesized from n-glucose derivatives containing a free hydroxyl group only in the 6-position. The 6-methyl ethers of D-mannose and of methyl a-n-mannoside were obtained similarly. Haworth and coworkers synthesized 2,3,4-trimethyl-n-glucose from 6-trityl-D-glucose and used the ether for the elucidation of structural problems. 

G. O. Aspinall, and G. Zweifel, Selective esterification of equatorial hydroxyl groups in the synthesis of some methyl ethers of D-mannose, J. Chem. Soc. (1957) 2271—2278. 

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