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Estra-4,9-dien-3-one

IODINE AND IODINE COMPOUNDS] (Vol 14) 17b-Hydroxy-llb-(4-dimethylaminophenyl-l)-17a-(prop-l-ynyl)-estra-4,9-diene-3-one... [Pg.497]

CN (lip,17 3)-ll-[4-(dimethylamino)phenyl]-17-hydroxy-17-(l-propynyl)estra-4,9-dien-3-one... [Pg.1333]

Antiprogestins, such as RU-486 (lift-hydroxy-11/3 (4 dimethylamino phenyl-1 )-17ry-(prop-l-ynyl)-estra-4.9-diene-3-one) (33) and ZK98299 1 l/J-(4-dimethylaminophenyl)-17a-hydroxy-17/j-(3-hydroxypropyl-13a-methyl-4,9-gonadien-3-one) represent a new class of drags for fertility regulation. Also, these drugs have potential applications in the treatment of uterine cancer. [Pg.1551]

Fig. 14.8. Chemical diagrams a diethylstilbestrol b f-pseudo-diethylstilbestrol, EPD c Z-pseudo-diethylstilbestrol, ZPD d /rows-tamoxifen e medroxyprogesterone acetate f 17a,21-dimethyl-19-nor-4,9-pregnadiene-3,20-dione (R5020) g 1 lyS-(4-(dimethyl-amino)phenyl)-l7J8-hy-droxy-17a-(l-propynyl)estra-4,9-dien-3-one (RU38486) h flutamide i l7j8-hydroxy-17a-methyl-4,9,1 l-estratrien-3-one... Fig. 14.8. Chemical diagrams a diethylstilbestrol b f-pseudo-diethylstilbestrol, EPD c Z-pseudo-diethylstilbestrol, ZPD d /rows-tamoxifen e medroxyprogesterone acetate f 17a,21-dimethyl-19-nor-4,9-pregnadiene-3,20-dione (R5020) g 1 lyS-(4-(dimethyl-amino)phenyl)-l7J8-hy-droxy-17a-(l-propynyl)estra-4,9-dien-3-one (RU38486) h flutamide i l7j8-hydroxy-17a-methyl-4,9,1 l-estratrien-3-one...
Cortexolone (4-pregnene-17,21-diol-3,20-dione), a partial agonist of the glucocorticoid receptor, and RU 38 486 [17P-hydroxy-lip-(4-dimethylamino-phenol) 17a-(prop-l-ynyl)estra-4,9-diene-3-one], a pure antagonist, were able to modulate and partially inhibit the suppressive effect of dexamethasone on the induction of NO2 in specific pathogen-free male Wistar rat alveolar macrophages (Jorens et al. 1992). [Pg.282]

RU-486 is a product of a French company, Roussel-Uclaf. Chemically, it should be named asll-(4-dimethylaminophenyl)-17-hydroxy-(proylynyl)-estra-4,9-diene-3-one. When used in conjunction with a synthetic prostaglandin, RU-486 has been... [Pg.106]

See other pages where Estra-4,9-dien-3-one is mentioned: [Pg.444]    [Pg.33]    [Pg.1723]    [Pg.288]    [Pg.2309]    [Pg.1723]    [Pg.444]    [Pg.618]    [Pg.1237]    [Pg.444]    [Pg.271]    [Pg.1036]    [Pg.205]    [Pg.159]    [Pg.299]   
See also in sourсe #XX -- [ Pg.33 ]

See also in sourсe #XX -- [ Pg.33 ]



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