Estimation of GMO hazard

For laboratory scale operations, the system adopted in the UK is commonly known as the Brenner method which classifies a GMO on the basis of three factors  

ACCESS, the probability that the GMO, or the DNA contained within it, will be able to enter the human body and survive there 

EXPRESSION, a measure of the anticipated or known level of expression of the inserted DNA 

DAMAGE, a measure of the likelihood of harm being caused to a person by exposure to a GMO. 

Each factor is assigned a probability value and an overall value of the GMO hazard to human health and safety is calculated by multiplying the 

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