Esters multidentate ligands

There are a few documented examples of studies of ligand effects on hydrolysis reactions. Angelici et al." investigated the effect of a number of multidentate ligands on the copper(II) ion-catalysed hydrolysis of coordinated amino acid esters. The equilibrium constant for binding of the ester and the rate constant for the hydrolysis of the resulting complex both decrease in the presence of ligands. Similar conclusions have been reached by Hay and Morris, who studied the effect of ethylenediamine... 

Complexes containing the multidentate dentate ligands listed in Table 2 and those with less than three carbonyl ligands listed in Table 3 have also been prepared. Some of the multidentate ligands contained a nucleotide others an ester or acid side chain. Finally, some results from solvent or binding studies are listed in Table 4. 

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