Esterases major classes

Esterases that contribute to human drug metabolism fall into three major classes the cholinesterases (acetylcholinesterase, pseudocholinesterase, butyrylcholinesterase, etc.),... 

A major class of enzymes that catalyze hydrolytic cleavage reactions. Examples include esterases, phosphatases, sulfatases, nucleases, glycosidases, peptidases, protein-ases, and amidases. 

Ubiquitous glycosylated carboxylesterases (CarbE, EC 3.1.1.1), formerly named ali-esterases, are B-esterases belonging to the multigene enzyme superfamily of a/P hydrolases (Hosokawa and Satoh, 2006 Satoh and Hosokawa, 2006). In principle this class of isozymes plays a major role in pharmacokinetics by hydrolytic biotransformation of exogenous ester-drugs and ester-prodrugs. However, their physiological fimction still remains unclear (Satoh and Hosokawa, 2006). 

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