Ester of thymidine 5 -pyrophosphate

A mutant strain of Escherichia coli Y-10, defective in L-rhamnose synthesis, accumulates109 a considerable amount of thymidine diphosphate sugars. Three of them were identified110 as the esters of thymidine 5 -pyrophosphate with 6-deoxy-a-D-xyZo-hexopyranos-4-ulose (28), 6-deoxy-D-glucose, and D-fucose. The fourth component was found to be a 4-acetamido-4,6-dideoxy-D-galactose derivative111,112 (29) it occurs also in Pasteurella pseudotuberculosis102 and its... 

Thymidine 5 -(a-D-glucopyranosyl pyrophosphate) (4) and the analogous D-galactose derivative have been isolated from extracts of Pasteurella pseudo tuberculosis.102 The ester of thymidine 5 -pyro-phosphate with a-D-mannopyranose was found in an extract of Strep-tomyces griseus,14,103 and the occurrence of the D-ribosyl ester in the... 

Threitol, from polysaccharides, 87 Threonine, 258 Thymidine, 228, 231 6-phosphates, 220 pyrophosphate esters of, 221 5-triphosphoric acid, 228 —, 5-(rhamnosyl dihydrogen pyrophosphate), 219 Thymine, 2-thio-, 229 Thymol, 236... 

Esters of /3-D-mannopyranosyl pyrophosphates have not yet been prepared, and consequently their behavior in alkaline solution is unknown. However, thymidine 5 -(/3-L-rhamnopyranosyl pyrophosphate), in which the steric disposition of groups should be similar in the normal (1C) conformation of the glycosyl group (85), is cleaved readily under alkaline conditions.103... 

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