Erythrokinetic study

In erythrokinetic studies, both Fe and Cr have been measured by solid scintillation counting, but results have often been unsatisfactory. In particular, the major difficulties were encountered in the investigation of iron kinetics. 

In erythrokinetic studies, Fe and Cr could be simultaneously assayed by LSC with great accuracy. An illustrative example is shown in Fig. 3. 

Leiken, S., Eng, G., 1963. Erythrokinetic studies of the anemia of lead poisoning. Pediatrics 31, 996-1002. 

The study of erythrokinetics in man requires the use of appropriate isotopes to evaluate red cell production and destruction. Red cell production is generally investigated through studies of iron kinetics and Fe is the chosen isotope. Red cell destruction is cammonly evaluated through labelled red cell survival studies, and Cr is the most extensively employed label. These isotopes can be simultaneously. 

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