Erylus formosus

Erylus formosus [45], was also reported by Kulkami et al. [53]. As shown in Fig. (19), a common bifunctional nine-carbon aldehyde was used for both syntheses. Both syntheses started with the DHP monoprotection of 1,4-butanediol, followed by subsequent PCC oxidation to the corresponding aldehyde. Reaction of this butanal with (4-carboxybutyl)triphenylphosphonium bromide resulted in the corresponding THP protected olefinic acid that was further deprotected and esterified to the methyl ester. A second oxidization with PCC afforded the desired intermediate methyl 8-formyloct-5-enoate which secured the cis A5 double bond in the final targets, Fig. (19). The... 

Carballeira, N.M. and Negron, V. (1991) Identification and characterization of two new methyl-icosadienoic acids from Erylus formosus. J. Nat. Prod., 54, 305-309. 

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