Ervatamia Iboga alkaloids

In China, the bark and leaves are used for the treatment of fractures. The roots are used in Malaysia to recover from childbirth and exhaustion, and a paste of the plant is used to treat orchitis. The plant contains indole alkaloids such as conodurinine, 19 (S) hydroxyconoduramin, 19 (S)-hydroxyervahanine A, and related iboga alkaloid congeners, and like the species mentioned earlier, and in fact the genera Ervatamia, in general, would be worth investigating for serotoninergic activities (17). 

Iboga alkaloids are found in other genera [e.g., Conopha-ryngia, Ervatamia, Hazunta, Melodinus, Pagiantha, Pan-daca, Tabernaemontanae, and Voacanga (Apocynaceae). 

Catharanthine-Ibogamine-Cleavamine Group. The chemistry and pharmacology of alkaloids of Tabernanthe iboga have been reviewed." New extractions have resulted in the isolation of coronaridine (previously observed), voacangine, isovoacangine, and ibogamine from the bark of Ervatamia coronaria, coronaridine and 19-oxocoronaridine from the roots of Tabernaemontana... 

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