Erlenmeye-Plochl azlactone synthesis

Formation of 5-oxazolones (or azlactones ) (2) by intramolecular condensation of acylglycines (1) in the presence of acetic anhydride is known as the Erlenmeyer-Plochl azlactone synthesis. ... 

A variant of the Perkin reaction is the Erlenmeyer-Plochl-azlactone synthesis By condensation of an aromatic aldehyde 1 with an N-acyl glycine 5 in the presence of sodium acetate and acetic anhydride, an azlactone 6 is obtained via the following mechanism ... 

Erlenmeyer, E., Jr. Ann. 1893, 275, 1. Emil Erlenmeyer, Jr. (1864—1921) was bom in Heidelberg, Germany to Emil Erlenmeyer (1825—1909), a famous chemistry professor at the University of Heidelberg. He investigated the Erlenmeyer-Plochl azlactone synthesis while he was a Professor of Chemistry at Strasburg. 

Brooks, D. A. Erlenmeyer—Plochl Azlactone Synthesis in Name Reactions in Heterocyclic Chemistry, Li, J. J. Corey, E. J., Eds. Wiley Sons Hoboken, NJ, 2005, 229-233. (Review). 

This reaction is related to the Erlenmeyer-Plochl Azlactone Synthesis. 

He investigated the Erlenmeyer-Plochl azlactone synthesis while he was a Professor of Chemistry at Strasburg. The Erlenmeyer flasks are ubiquitous in organic chemistry laboratories. 

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