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Erhlich, Paul

The development of the "sulfa drugs,"a c derivatives of sulfanilamide, originated with studies of the staining of protozoal parasites by Paul Erhlich. In 1932 it was shown that the red dye 2,4-diamino-azobenzene-4 -sulfonamide (Prontosil) dramatically cured systemic infections by gram-positive bacteria. Subsequent studies revealed that bacteria converted... [Pg.473]

Arsenic was, without doubt, important in the successful treatment of S5q>hilis. The drug Salvarsan (arsphenamine) was discovered by Paul Erhlich during a systematic study of arsenic compounds for a potential cure for syphilis. Salvarsan is a synthetic organic chemical that contains arsenic he had tried more than 600 chemicals when he happened on this one. His quest was based on the behef that he could find a substance that was selectively toxic to the organism that causes syphilis (a spirochaete) but less toxic to the patient, a magic bullet . Only recently, arsenic trioxide (the form of arsenic commonly used for homicide) was licensed by the... [Pg.224]

Paul Erhlich tests salvarsan, first treatment effective against syphilis regarded as birth of modern chemotherapy... [Pg.16]

See other pages where Erhlich, Paul is mentioned: [Pg.916]    [Pg.916]    [Pg.93]    [Pg.45]    [Pg.64]    [Pg.93]    [Pg.11]    [Pg.254]    [Pg.255]   
See also in sourсe #XX -- [ Pg.473 ]

See also in sourсe #XX -- [ Pg.473 ]

See also in sourсe #XX -- [ Pg.473 ]

See also in sourсe #XX -- [ Pg.473 ]

See also in sourсe #XX -- [ Pg.226 ]

See also in sourсe #XX -- [ Pg.226 ]



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