Equine leukoencephalomalacia fumonisin

PF Ross, PE Nelson, JL Richard, GD Osweiler, LG Rice, RD Plattner, TM Wilson. Production of fumonisins by Fusarium moniliforme and Fusarium proliferatum isolates associated with equine leukoencephalomalacia and a pulmonary oedema syndrome in swine. Appl Env Microbiol 56 3225, 1990. 

In some regions where com is essential for human nutrition, the occurrence of esophageal carcinoma has been reported, and this has been associated with fumonisin contamination (211). Concerning the AAL-toxins (see previous section), these were found to be associated with human esophageal cancer, equine leukoencephalomalacia, and liver diseases in humans (272). In the laboratory, these compounds have been shown to inhibit sphingolipid synthesis (213) and to cause apoptosis in tomato cells and green monkey kidney cells (214, 215). 

Thiel PG, Shepherd GS, Sydenham EW, Marasas WFO, Nelson PE, Wilson TM (1991) Levels of Fumonisin B1 and B2 in Feces Associated with Confirmed Cases of Equine Leukoencephalomalacia. J Agric Food Qiem 39 109... 

---