Epilepsy preventive interventions

Interestingly, many forms of partial epilepsy are characterized by a seizure-free interval lasting months to years between the occurrence of the causative insult and the emergence of epilepsy termed the latent period , this provides a valuable window of opportunity during which pharmacologic intervention might be implemented in high-risk individuals so that development of epilepsy could be prevented. 

This mutant line will be a useful model for testing the effectiveness of pharmacological intervention in preventing cell loss, an important goal of epilepsy treatment in human patients. Since other Na" " channels are also expressed in hippocampal neurons, it seems likely that delayed inactivation of SCN1A, SCN3A or SCN8A could also result in seizures. 

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