Epigallocatechin gallate plasma concentrations

The concentration of 4, 4"-di-0-methyl-epigallocatechin gallate was about 15% that of unmethylated epigallocatechin gallate in human plasma. It is likely that the gallated flavan-3-ols produce numerous combinations of conjugated metabolites. The structures of the predominant forms of these metabolites in plasma after green tea consumption need to be determined. 

Figure 8.5 Average plasma concentration versus time curves drawn from literature survey. Data were converted to correspond to a single dose of 50 mg aglycone equivalent, (a) isoflavone agly-cones (b) isoflavone glucosides (c) quercetin glucosides (d) quercetin rutinoside (e) flavanone glycosides (f) (epi)catechins (g) (—)-epigallocatechin gallate (h) anthocyanins.

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