Enzyme-triggered enantioconvergent cascade reaction

Figure 6.69 An enantioconvergent enzyme-triggered cascade reaction.

Enantioconvergent enzyme-triggered cascade reaction of rac-c/s-1-chioro-2,3-epoxyheptane as a key step for the total synthesis of a (+)-Jamaican rum constituent and (+)-pestaiotin. 

Mayer, S.F., Steinreiber, A., Goriup, M., Saf, R. and Faber, K. (2002) Chemoenzymatic asymmetric total syntheses of a constituent of Jamaican rum and of (+)-Pestalotin using an enantioconvergent enzyme-triggered cascade reaction. Tetrahedron Asymmetry, 13, 523-528. 

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