Enzymatic monooxygenation reactions

Polymer Modification by Oxidoreductases. Tyrosinase (polyphenol oxidase, a copper-containing monooxygenation enzyme) was used as catalyst for modification of chitosan. The enzymatic treatment of chitosan film in the presence of tyrosinase and phenol derivatives produced a new material of chitosan derivative (309). During the reaction, imstable o-quinones were formed, followed by the reaction with chitosan to give the modified chitosan. In the enzymatic treatment of p-cresol with a low concentration of chitosan (<1%), the reaction solution was converted into a gel (310). 

It should be emphasized that investigations of embryonic enzymatic catalysis of the four retinoid biotransforming reactions (2ill-trans/9-cis isomerization, retinol and retinal dehydrogenation, glucuronidation and monooxygenation) have been numerous [6,7,10-13,15,18-22, 77-85]. 

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