Environmental Degradation, Ecotox and Tox

Both cloransulam-methyl and diclosulam have low acute toxicology profiles and no indication of any chronic toxicology issues. Both compounds do show slight toxicity to Daphnia but are considered practically non-toxic to birds, insects, aquatic organisms and earthworms. 

Florasulam (5) dissipates primarily through microbial degradation [22]. Other patterns of degradation or dissipation contribute minimally to the loss of florasu- 

The overall toxicological profile of florasulam is very favorable. It is not acutely toxic, does not pose an inhalation hazard, nor is it a skin sensitizer. No evidence of mutagenic or carcinogenic potential was obtained from any study. It showed no teratogenic effects in either rats or rabbits. Tests also indicate that florasulam is not a reproductive hazard or concern. 

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