Enolate Equivalents from a-Functionalized Aldehydes

In 2012, Sun and co-workers documented an enantioseleetive synthesis of P,y-unsaturated a-fluoro esters catalyzed by NHC. Chiral NHC prepared in situ by the reaction of the corresponding triazolium chloride with sodium 

In 2014, the Ye group delivered a novel y-amination by NHC-catalyzed [4 + 2] annulation of oxidized enals and azodicarboxylates giving the corresponding dihydropyridazinones in good yields with excellent enantiose-lectivity. It is envisioned that the addition of an NHC to enals having a 

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