Endovascular prostheses

Transluminally Placed Endovascular Prostheses (Stent-Grafts)... 

Endovascular prosfheses, assembled from tubular textile fabric and wire stent components, are deployed and expanded non-invasively from catheters for the rq>air of aneurysms in medium and large caliber arteries. Now that the implantation procedure is no longer experimental and these devices are becoming widely accepted and used for a growing cohort of patients, so the incidence of reported cases of late complications continues to grow. Observations from our own implant retrieval programme have led us to report that certain styles and models of endovascular prostheses are associated with particular failure mechanisms, such as endoleaks, migration, thrombosis, stent disruption, as well as fabric distortion and perforation. 

A series of tubular fabric samples, typical for use in endovascular prostheses, were woven from polyester monofilament and multifilament yams on a special narrow ribbon shutde loom. They were 8 mm in diameter and 6 cm in length, and bad the structural specifications listed in Table 1. 

Z Shuyao, L Yuling, Research and development of endovascular prostheses and their performances . Master Degree Thesis, Donghua University, Shang hai, P.R. China, 2003. 

Sumanasinghe, R.D. (2003) Stability of Poly (ethylene terephthalate) Endovascular Prostheses to Hydrolytic and Enzymatic Degradation. Master thesis. North Carolina State University. 

Endovascular prostheses for aortic aneurysms a new era for vascular surgery... 

Antonucci F, Salomonowitz E, Stuckmann G et al. (1992) Hemodialysis related venous stenoses treatment with self-expanding endovascular prostheses. Eur J Radiol 14 195-200 Bartorelli AL, Fabbiocchi F, Montorsi P et al. (1995) Successful transcatheter management of Palmaz stent embolization after superior vena caval stenting. Cathet Cardiovasc Diagn 34 162-166... 

One relevant application involves vascular stents (endovascular prostheses), where thrombosis and restenosis remain a problem. So far, drug eluting coatings have been developed and applied with mixed results. One therapeutical approach involved ion implantation and cyclotron activation of stents to render them radioactive so as to inhibit neointimal formation and reduce restenosis, e.g. ion implantation to subsequently obtain radioactive or direct P ion implantation. 

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