Endonuclease snake venom

Endonuclease. Snake venoms do possess endopolynucleotidase activities thus they can hydrolyze RNAand DNA, producing oligonucleotide fragments. The important question is whether snake venom contains specific RNase or DNase like pancrease, or whether the hydrolysis is due to a nonspecific endonuclease that has not been isolated in pure form. 

B. Phosphodiesterase. Snake venoms commonly contain enzymes that hydrolyze phosphodiester bonds. There are two types of phosphodiesterase one is an exonuclease and the second is an endonuclease. 

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