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Homing endonucleases

Chevalier, B.S. Stoddard, B.L. (2001) Homing endonucleases structural and functional insight into the catalysts of intron/intein mobility. Nucleic Acid Res. 29, 3757-3774. [Pg.1032]

Why do cells ever splice proteins It isn t clear. However, a curious fact is that many inteins are homing endonucleases.h k The genes for these nucleases are often present in introns in mRNA, and the homing endonuclease often cuts DNA in such a way as to initiate movement of its own gene (Chapter 27). The endonuclease itself is found in the center of the intein between the two end domains, which contain the catalytic centers for the splicing reaction. [Pg.1717]

Smith J, Grizot S, Amould S, Duclert A, Epinat JC, Chames P, Prieto J, Redondo P, Blanco FJ, Bravo J, Montoya G, Paques F, Duchateau P (2006) A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences. Nucleic Acids Res 34 el49... [Pg.130]

The DnaB intein from Synechocystis spp. consists of 429 amino acids, including a homing endonuclease domain, in its native form. The removal of 275 amino acids leads to... [Pg.1790]

Jurica MS, Stoddard BL (1999) Homing endonucleases structure, function and evolution. Cell Mol Life Sci 55 1304-1326... [Pg.218]

Stoddard BL (2005) Homing endonuclease structure and function. Q Rev Biophys 38 49-95... [Pg.218]

S. Fujiwara, M. Takagi, T. Imanaka, T. In-oue, Y. Kai, Crystallographic study of intein homing endonuclease II encoded in the ar-chaeal DNA polymerase gene, Acta Crys-tallogr. D Biol. Crystallogr. 2000, 56 (Pt 9), 1185-1186. [Pg.93]

See other pages where Homing endonucleases is mentioned: [Pg.110]    [Pg.294]    [Pg.309]    [Pg.1024]    [Pg.1025]    [Pg.1025]    [Pg.1025]    [Pg.1025]    [Pg.1025]    [Pg.1657]    [Pg.1716]    [Pg.54]    [Pg.55]    [Pg.70]    [Pg.123]    [Pg.130]    [Pg.107]    [Pg.355]    [Pg.204]    [Pg.22]    [Pg.80]    [Pg.309]    [Pg.1024]    [Pg.1025]    [Pg.1025]    [Pg.1025]    [Pg.1025]    [Pg.1025]    [Pg.744]    [Pg.803]    [Pg.723]    [Pg.782]    [Pg.13]    [Pg.51]   
See also in sourсe #XX -- [ Pg.1717 ]



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Endonucleases

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