Enantiotopic ligands definition

Enantiotopic ligands definition, 359 Enantio-zeroplane definition, 359 endo/exo-Selective reactions ... 

The two protons at C(l) are topologically nonequivalent, since substitution of one produces a product that is stereoisomerically distinct from that produced by substitution of the other. Ligands of this type are termed heterotopic, and, because the products of substitution are enantiomers, the definition can be made more precise.Ligands that on substitution produce enantiomers are enantiotopic. If a chiral assembly is generated when a point ligand is replaced by a new point ligand, the original assembly is prochiral Both C(l) and C(3) of 1,3-propanediol are prochiral centers. 

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