Enantiomeric cross-inhibition

Lente proposed a discrete-state stochastic modeling approach in which chiral amplification could be described by a quadratic autocatalytic model without considering cross-inhibition [67,68]. However, the discrepancy between the usually employed deterministic kinetic approach, which reinforces the need for cross-inhibition, and the discrete-state stochastic approach is only apparent. The discrete approach considers the repetitive reproduction of single molecules which, in the case of a chiral system, obviously are individually all enantiomerically pure. Hence, basically no amplification of the ee occurs at all during the discrete scenario. It has been indicated that deter-... 

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