Electrospinning emulsion

Xu, X. Zhuang, X. Chen, X. Wang, X. Yang, L. Jing, X. Preparation of core-sheath composite nanofibers by emulsion electrospinning. Macromol. Rapid Commun. 2006, 27 (19),1637-1642. 

J.A. Smolen, Emulsion electrospinning fa- producing dome-shaped structures within 1-tyrosine polyurethane scaffolds for gene delivery. Master s Thesis, The Univosity of Akron, Akron, OH, 2010. 

Emulsion electrospinning and mainly coaxial electrospinning have been widely employed to produce this kind of scaffold in order to promote a better control of release kinetics (Figure 7.5). In emulsion electrospinning, the biomolecule is solubilized in an aqueous solution normally containing a protein, such as albumin. 

PLLA BMP2 Emulsion electrospinning Production of osteoconductive scaffolds for bone repair [155]... 

A novel technique combining coaxial and emulsion electrospinning was presented to produce microstructured core-shell fibers. The design of micro drug reservoirs of variable size within the bulk of fibers combined with a tailored diffusive barrier allows modulating the release kinetics of these novel carriers. A... 

Yang, Y., Li, X.H., Cui, W.G., Zhou, S.B., Tan, R., and Wang, C.Y. (2008) Structural stability and release profiles of proteins from core-shell poly(DL-lactide) ultrafine fibers prepared by emulsion electrospinning. /. Biomed. Mater. Res. A, 86A, 374-385. 

Emulsion electrospinning can be also used. Maretschek et al. produced protein-loaded nanofibre non-wovens based on PLLA via emulsion electrospinning. As the hydrophobicity of the non-woven nanofibres affects the release of macromolecules, PLLA was blended with hydrophilic polymers such as poly(ethylene imine) and poly(L-lysine) to modify the release profiles, resulting in an increase in fibre diameter and a decrease in the specific surface area and highly hydrophobic surfaces. 

Figure 5.15 Schematic mechanism for the formation of core-sheath composite fibers during emulsion electrospinning [67]...

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