Embolic applications of shape memory polyurethane scaffolds

1 Department of Biomedical Engineering, Texas A M University, College Station, TX, USA Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA, USA 

SMPs can be fabricated using a variety of polymer systems, including poly( -capro-lactones), acrylates, polynorbomenes, cross-linked polyethylenes, poly(ether ketones), and polyurethanes (Defize et al., 2011 Hearon et al., 2011 Khonakdar et al., 2007  

The best-suited technique for fabricating a given scaffold depends on the intended application, the polymers being used in the fabrication, and the conditions under which the polymer solutions are cured and maintained. Some of these fabrication techniques 

Neat polymers have been used extensively for drug delivery applications and as biomaterials that promote cell adhesion. In fact, some of the earliest polymer scaffolds were simply films that promoted cell adhesion and growth (Ito et al., 1991). Aljawish et al. synthesized surface-modified chitosan films and studied the degree of protein adsorption and cell adhesion onto the substtate. Heterogeneous surface morphology of the films improved protein adsorption and subsequently resulted in favorable cell attachment and spreading (Aljawish et al., 2014). Film thickness also played a role in increasing cell viability. It was discovered that thicker films resulted in better cell viabihty (Aljawish et al., 2014). 

A side material polyols, water, surfactants, catalysts 

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Embolic applications of shape memory polyurethane scaffolds... 

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