Embden-Meyerhof-Pamas pathway

Glycolysis, also called as Embden-Meyerhof-Pamas pathway (EMP pathway). Glycolysis is of central importance to the metabolism of eukaryotic cells. It links the metabolism of sugars to that of organic acids in the Krebs cycle, and in anaerobic organisms, provides the principle route of energy (ATP) generation. The reactions are rather complex, but can be seen as four basic processes (Fig. 9.2) ... 

Figure 17-9 Reaction sequences in fermentation based on the Embden-Meyerhof-Pamas pathway. Oxidation steps (producing NADH + H+) are marked "O" reduction steps (using NADH + H+) are marked "R."...

The generic dynamic model for the bioparticle, where the kinetic expressions are adapted of Rotboll and Jorgensen [9] is given by Eq. 3. In the model, [ ] represents a generic concentration. Substrate conversion in the pellet through the reactions of the Embden-Meyerhof-Pamas pathway forms intermediates such as acetaldehyde [A] and pyruvate [P] that are reduced to ethanol [ ] or oxidized in the steps of the TCA pathway. 

Fig. 17.2 The Embden-Meyerhof-Pamas pathway (glycolytic pathway).

Obligately homofermentative Exclusively ferment hexoses and produce lactic acid by the EMP (Embden-Meyerhof-Pamas) pathway... 

The mechanism of fusel oil production from carbohydrates follows the typical Embden-Meyerhof-Pamas pathway to pyruvic acid. Pyruvic acid may be reacted with a second pyruvic acid to yield acetolactic acid. Acetolactic acid enters the valine-isoleucine biosynthesis pathway and is converted to a-keto isovaleric acid. The a-keto isovaleric acid may then be reduced to isobutyl alcohol or isobutyric... 

Embden-Meyerhof-Pamas pathway Figure 15.9 Biocompatibility of PLA. 

In bacteria, the metabolism of o-xylose uptake is quite different from the one for D-glucose, which occurs by the Embden-Meyerhof-Pamas pathway (Jeffries 1983). D-xylose is degraded by the pentose phosphate pathway (PPP) (also called hexose monophosphate pathway, pentose phosphate shtmt, phosphogluconate pathway) after being transported into the cell. Once inside the cell, it is either isomerized or reduced and then reoxidized to form o-xylulose. Further steps lead to phosphory-lated 3-, 4-, 5-, 6-, and 7-carbon sugars. Intermediates can then be used by other metabolic pathways to produce nucleic acids, aromatic amino acids, hpids, and other metabolic end products (Jeffries 1983). 

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