Electrostatic droplet generation effects

F. Effects of Electrostatic Droplet Generation on Cell Viability. 883... 

Analyte ions can also be efficiently generated when sample vapor or finely dispersed sample droplets transported by a carrier gas stream are admixed to the expanding electrospray plume. This technique, simple yet effective, has been introduced as extractive electrospray ionization (EESI) [37]. It utilizes two separate sprayers, one conventional ESI sprayer to provide the electrostatically charged mist and another to supply the sample vapor or mist (Fig. 13.13). While this approach is suggested for API interfaces with the heated transfer capillary design, the sample carrier stream may alternatively be passed into the desolvation gas of interfaces employing the heated curtain gas design (Fig. 13.14) [6,38]. 

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