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Electrophilic substitution is the usual route to substituted aromatic compounds

Electrophilic substitution is the usual route to substituted aromatic compounds [Pg.576]

One complete synthesis is shown as the conclusion of this chapter. It is here to demonstrate that manipulation of simple aromatic rings is very much part of modern organic chemistry and because almost all the reactions are ones you have seen so far in the book. [Pg.576]

1 The starting material was chosen because it was cheap. It has the right number of substituents in the right places but only one (MeO-) is still there at the end [Pg.576]

3 Step 3, the hydrolysis of the ester, and step 6, amide formation, are familiar reactions [Pg.576]

4 Step 2, the replacement of OH by Cl, wiU be discussed in Chapter 23 as it is a nucleophilic aromatic substitution [Pg.576]




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Aromatic compounds substituted aromatics

Aromatic compounds substitutents

Aromaticity electrophilic aromatic substitution

Aromatics electrophilic substitution

Electrophile Electrophilic aromatic substitution

Substituted Compounds

Substitution compounds

Substitution electrophilic aromatic

Substitution electrophilic aromatic substitutions

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