Electrophilic aromatic substitution regiochemistry prediction

Presumably, the oxidative cyclization of 3 commences with direct palladation at the a position, forming o-arylpalladium(II) complex 5 in a fashion analogous to a typical electrophilic aromatic substitution (this statement will be useful in predicting the regiochemistry of oxidative additions). Subsequently, in a manner akin to an intramolecular Heck reaction, intermediate 5 undergoes an intramolecular insertion onto the other benzene ring, furnishing 6. (i-Hydride elimination of 6 then results in carbazole 4. [Pg.3]

Predicting the Effect of a Substituent on the Rate and Regiochemistry of an Electrophilic Aromatic Substitution Reaction... [Pg.671]

Predict the effect of these substituents on the rate and regiochemistry of electrophilic aromatic substitution reactions ... [Pg.680]

Predict the effect of a substituent on the rate and the regiochemistry of an electrophilic aromatic substitution reaction. [Pg.283]

Working with the Concepts Predicting Regiochemistry in Electrophilic Aromatic Substitutions... [Pg.704]

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