Electrokinetic chromatography retention factor

Another relatively new lipophilicity scale proposed for use in AD ME studies is based on micellar electrokinetic chromatography (MEKC) [113]. A further variant is called biopartitioning micellar chromatography (BMC) and uses mobile phases of Brij35 (polyoxyethylene(23)lauryl ether) [114]. Similarly, the retention factors of 16 beta-blockers obtained with micellar chromatography using sodium dodecyl sulfate... [Pg.85]

In micellar electrokinetic chromatography and microemulsion electroMnetic chromatography, the retention factor kf of a neutral compound is defined as [Muijselaar, Claessens et al., 1994]... [Pg.137]

From this retention factor, the Migration Index (MI) for a compound in microemulsion electrokinetic chromatography was defined as [Ishihama, Oda et al., 1996]... [Pg.137]

The apparent electrophoretic mobility of an analyte in micellar electrokinetic chromatography depends on three factors the electroosmotic mobility for the system the fraction of analyte in the electrolyte solution and its electrophoretic mobility and the fraction of analyte in the pseudostationary phase, and the electrophoretic mobility of the micelles (assuming that the mobility of the analyte-micelle complex is the same as the micelle). If we introduce the chromatographic retention factor, defined as the ratio of the number of analyte molecules in the pseudostationary phase to the number in the... [Pg.645]

The general resolution equation for two neutral analytes with similar retention factors in micellar electrokinetic chromatography, is similar to the relationship for chromatography (section 1.6) with an additional term that arises from the limited migration time window [11,12,166,177,178]. [Pg.649]

Lucangioli, S., Kenndler, E., Carlucci, A., Tripodi, V., Scioscia, S., and Carducci, C. 2003, Relation between retention factors of immunosuppressive drugs in microemulsion electrokinetic chromatography with biosurfactants and octanol-water partition coefficients. J. Pharm. Biomed. Anal. 33, 871. [Pg.522]

Lucangioli, S., Carducci, C., Tripodi, V., Kenndler, E. and 2001, Retention of bile salts in micellar electrokinetic chromatography Relation of capacity factor to octanol-water partition coefficient and critical micellar concentration. J. Chromatogr. B 765, 113. [Pg.523]