Effectiveness of an Ideal Carrier

Similar equations have been derived by other authors, using various types of compart-mental models [40,48] (Section 13.2.4.1) or simplified physiological models [44,45,48] (Section 13.2.4.2), demonstrating that the choice of the model is not critical in the derivation of 

Apart from drugs directed at hepatocytes and renal tubular cells, in the case of the majority of conventional drugs, it is likely that the drug is not eliminated directly from the target site, and therefore r = 0, which further simplifies Eq. 13.24 to  

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