Effect of average pore size

The optimal separation power of a sw port vdll theoretically be obtained at half the average pore size (see Egn. 12). The maximal selectivity m be derived for a single pore size support from Btyi. 6 cis 

The selectivity may be converted into terms of molecular wei t of various solutes by using the repressions given in Table 1. The maximal selectivity of a support is thus 0.7 per decade in molecular weic. As Kwn tiy Yau et al., the pore sh (i.e., cylindrical or open-slab pores) has only a small influence on the selectivity of the support (107). For a single pore size support the -range 0.1 to 0.9 will oorreqxxid to a solute size ratio 

When considering the effect of pore size on exclusion of solutes, the flexibility of the solute molecule mist also be taken into cKxxxmt. Flexible molecules may change their conformation and thus partly penetrate pores idilch are smaller than the hydrodynamic radius of the solute. This effect is 

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