Edman, Pehr Victor

Eclipsed conformation, 94 molecular model of, 94 Edman, Pehr Victor, 1031 Ed man degradation, 1031-1032 mechanism of. 1032 Eicosanoid, 1067-1070... 

Edman, Pehr Victor (1916-1977), a pioneer in the field of peptide and protein chemistry. Already for his Ph.D he had isolated and purified angiotensin. In 1947, he accepted an associate professorship at the University of Lund (Sweden), and in 1957 Edman came to Melbourne as the first John Holt director of research at St. Vincent s School of Medical Research. In 1972, he moved to Germany, having been appointed Professor at the Max-Planck-Institute for Biochemistry at Martinsried. He is the inventor of an important method for protein structure determination, named the Edman degradation [F. J. Morgan, Edman, Pehr Victor (1916-1977), Austr. Diet. Biograph. 1996, Volume 14, pp. 78-79]. 

Edman, Pehr Victor, 1916-1977 (pp. 118,240, Plate 15) born in Stockholm in 1916, matriculation examination in 1935, studied medicine at the Karolinska Institute Medical School in Stockholm from 1935, Bachelor of Medicine in 1938, graduation as a physician in 1946. Concurrently with his studies in medicine he started his training in biochemistry with Erik Jorpes, for a short time also with Hugo Theorell, and soon started a project on angiotensin that led to a MD thesis. Then he widened his experience in protein chemistry during one year at the Rockefeller Institute in Princeton with Northrop and Kunitz (crystallization of proteolytic enzymes). On his return to Sweden, Edman was awarded an associate professorship in Lund in 1947 where he conducted his stepwise peptide degradation work (p. 118) between 1950 and 1956. In 1957 Pehr Edman accepted an offer to be Director of Research at St. Vincent s School of Medical Research in Melbourne, Australia, where he remained for 15 years, during which the work on an automated sequence analyzer was finished in 1967. From 1972 until his death from a brain tumor in 1977 he was Director of the Department of Protein Chemistry of the Max-Planck-Institute for Biochemistry in Martinsried near Munich. 

Pehr Victor Edman (1916 1977) was born in Stockholm, Sweden, and received an M.D. in 1946 at the Karolinska Institute, After a year in the United States at the Rockefeller Institute, he returned to Sweden as professor at the University of Lund. In 1957, he moved to St. Vincent s School of Medical Research in Melbourne, Australia, where he developed and automated the method of peptide sequencing that bears his name. A reclusive man, he never received the prizes or recognition merited by the importance of his work. 

Plate 14. Victor Bruckner (1900-1980) Plate 15. Pehr V. Edman (1916-1977)... 

---