Ear Otic Agents

Aluminum Acetate (Otic Domeboro) Benzocaine Antipyrine (Auralgan) 

Magnesium Sulfate (various) Multivitamins (Table VI-6) Phytonadione [Vitamin K] (Aqua-MEPHYTON) Potassium Supplements (Kaon, Kaochlor, 

Ciprofloxacin, Otic (Cipro HC Otic) Polymyxin B Hydrocortisone (Otobiotic Otic) 

Slow-K, Micro-K, Klorvess, others) (Table VI-5) Pyridoxine [Vitamin B6] Thiamine [Vitamin BJ 

Sulfacetamide Prednisolone (Blephamide, others) Triethanolamine (Cerumenex) 

Aluminum Acetate (Ode Domeboi-o) Benzocaine Andpyrine (Auralgan) 

Ciprofloxacin, Ode (Cipi-o HC Ode) Polymyxin B Hydi ocordsone (Otobiodc Ode) 

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Despite similar antibacterial composition, ototopical preparations may differ in delivery vehicle and pH level. Cortisporin Otic solution is the most acidic, whereas Coly-Mycin S Otic has a pH of 5, the highest of the group. The low pH of these compounds and the alcohol used as an antiseptic agent cause a burning sensation when in contact with the middle ear. 

Nurses, who have many opportunities to come into contact with disinfecting agents such as benzalkonium chloride, are frequently affected [60-62]. There are two reports of an allergy developing after cast material containing benzalkonium chloride was used to set broken bones [63, 64]. Ophthalmologic and patients with external ear infections are also sometimes affected, as benzalkonium chloride is used in ophthalmologic and otic preparations [57, 65, 66]. 

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