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Dysregulated innate immune system

The pathogenesis of alcoholic liver disease is a multifactorial process involving metabolic repercussions of ethanol oxidation in the liver, dysregulation of fatty acid oxidation and synthesis, and activation of the innate immune system by a combination of direct effects of ethanol and its metabolites and by bacterial endotoxins that access the liver as a result of ethanol-induced changes in the intestinal tract. Tumor necrosis factor- , a proinflammatory cytokine that is consistently... [Pg.495]

See other pages where Dysregulated innate immune system is mentioned: [Pg.292]    [Pg.292]    [Pg.1328]    [Pg.332]    [Pg.419]    [Pg.124]    [Pg.24]    [Pg.599]    [Pg.215]    [Pg.644]   
See also in sourсe #XX -- [ Pg.292 ]



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