4,8,13-duvatrien-l,3-diol

Ripperger H, Schreiber K, Budzikiewicz H (1967b) IsoUerung von Neochlorogenin und Pemiculogenin aus Solarium paniculatum L. Ber 100 1741-1752 Roberts DL, Rowland RL (1962) MacrocycUc diterpenes a- and P-4,8,13-duvatriene-l,3-diols from tobacco. J Oig Chem 27 3989-3995... 

A regular diamond lattice conformation was found for cyclotetradecanone at —157 °C. The structures of sinulariolide (27)" and a plant-growth inhibitor found to be 4,8,13-duvatriene-l,3,-diol(28) have been confirmed using X-ray methods. 

Cuticular extracts used for the isolation of components were obtained from different N. tabacum genotypes that were grown in blocks of 100 plants. Cuticular components were extracted from plant tops using methylene chloride as previously described (75). The extracts from the following tobaccos were used to isolate specific components using the methodology reported by Severson et al.(76) a- and B-4,8,13-duvatriene-l,3-diols (DVT-diols) (97+% by GC, 3 1 a-diol to B-diol) from NC 2326 a- and B-4,8,13-duvatrien-l-ols (DVT-ols) (98+% by GC, 9 1 a-ol to B-ol) from PD 1097 a sucrose ester fraction (SE, 6-O-acetyl-2,3,4-tri-0-acyl-sucrose) (97+%by GC) from PD 1097 labda-12,14-dien-8a-ol (cw-abienol) (98+% as monohydrate, mp 67 C) from NET and labda-13-ene-8a,15-diol(labdenediol) (99+%, mp 126-128 C) from PD 964. 

Figure 1. Probit analyses for survival rates of tobacco aphids that were topically dosed with components isolated from tobacco germplasm sources (N=60 aphids per dose Regression R s Nicotine, 0.75 Sucrose Esters, 0.66 Cw-Abienol, 0.73 a- and B-4,8,13-duvatriene-l,3-diols (DVT-diols), 0.98 a- and B-4,8,13-duvatrien-l-ols (DVT-ols), 0.98 DVT-ols + Cw-abienol, 0.90).

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