Duranta repens

Within the complex flavonols, C-5 substitution is by far the most prominent trend in terms of numbers of compounds and sources. Also, the number of structurally different C-5-residues is remarkable. Apart from the common 3,3-dimethylallyl and the rarer 1,1-dimethylallyl, several hydroxylated C-5-residues such as in topazolin hydrate, isolated from roots of Lupinus luteus (Fabaceae compound 94 in Table 12.4). Another source of such compounds is the whole plant of Duranta repens (Verbenaceae). Plant organs accumulating C-prenylflavo-nols range from buds to leaves and from aerial parts to roots. Only the bud constituents may be considered as exudate compounds. From Lilium candidum, a more complex flavonol was reported (Figure 12.8). This genus also accumulates N-containing flavonoid derivatives discussed earlier. ... 

Anis, I. et al.. Thrombin inhibitory constituents from Duranta repens, Helv. Chim. Acta, 84, 649, 2001. 

Iqbal et al. studied the phosphodiesterase inhibitory effect of durantins A (33), B (15), and C (16), isolated from Duranta repens (70). Compounds 16 and 33, along with compound 9, showed moderate to strong inhibitory activity against snake venom phosphodiesterase 1, using cysteine and EDTA as positive controls, while 15 showed weak activity. 

Iqbal K, Anis I, Mukhtar N, Malik A, Fatima N, Choudhary MI (2003) Phosphodiesterase Inhibitory Coumarinolignoids from Duranta repens. Heterocycles 60 151... 

Dasiphora jruticosa Cynoglossum divaricatum and C. officinale Dimorphandra mollis Duranta repens... 

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