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Recent data in our laboratories indicated the possible involvement of central and peripheral dopamine binding sites in the pathogenesis of duodenal ulceration. Structure activity studies with duodenal ulcerogens implicated dopamine as a putative mediator and/or modulator in duodenal ulceration. Using the cysteamine- or propionitrile-induced duodenal ulcer model in rats, we found that dopamine agonists (e.g., bromocriptine, lergotrile,... [Pg.175]

See other pages where Ulcerogens, duodenal, structure is mentioned: [Pg.176] [Pg.176] [Pg.177] [Pg.180] [Pg.191] [Pg.191] [Pg.164] [Pg.177]