Dual domain approach

The midplane FE approach is by far the most efficient numerical method for the simulation of injection molding of thin-walled parts. However, the preparation of a midplane mesh can take a considerable amount of time. 

The limitations of the automatic midplane generation stimulated the innovation of the so-called dual domain approach (Yu and Thomas 2000 Yu et al. 2004). This approach uses the external mesh on a 3-D geometry. It still solves the Hele-Shaw equation but eliminates the need for a midplane mesh. 

The dual-domain technique is still classified as a 2.5D simulation. 

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A graphical approach was also used by Millet and Pons to analyse anisotropy of rotational diffusion in proteins. The values of Z)j and DJD compatible with R IRi ratios are presented as a contour plot. The intersection of the contour plots for different residues provides the values of anisotropy parameters compatible with experimental data. The obtained parameters can be used as starting values for further optimisation. The method is apphcable to axially symmetric rotation. A combination of approximate and exact methods was used by Ghose et al. to reduce the computational time of the determination of rotational diffusion tensor from NMR relaxation data. The initial values of the tensor components and its orientation are evaluated from the approximate solution, which substantially reduces the search space during the exact calculations. The method was applied for the estimation of relative domain orientation of a dual domain protein. 

Time domain aliasing cancellation based filter banks. The Modified Discrete Cosine Transform (MDCT) was first proposed in [Princen et al., 1987] as a sub-band/transform coding scheme using Time Domain Aliasing Cancellation (TDAC). It can be viewed as a dual to the QMF-approach doing frequency domain aliasing cancellation. The window is constructed in a way that satisfies the perfect reconstruction condition ... 

Grucza RA, Bradshaw JM, Fiitterer K, Waksman G. SH2 domains From structure to energetics, a dual approach to the study of structure—function relationships. Med. Res. Rev. 1999 19 273-293. 

Multiple groups have taken an alternative approach to this problem by using recombinant techniques to add an additional antigen recognition site to both Fab domains of an IgG. This addition allows for simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin. Wu et al. report that such an approach provides therapeutic proteins with high potential of success for the treatment of human diseases. ... 

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