Intravaginal veterinary drug delivery systems

Rathbone, M. J., Macmillan, K. L., Bunt, C. R., and Burggraaf, S. (1997), Conceptual and commercially available intravaginal veterinary drug delivery systems, Adv. Drug Deliv. Rev., 28, 363-392. 

Table 2 Factors Affecting Design of an Intravaginal Veterinary Drug Delivery System...

Several factors affect the design and development of an intravaginal veterinary drug delivery system. These are listed in Table 2 (13). 

Several drug delivery systems of intravaginal veterinary delivery systems are commercially available (Fig. 9), and include... 

A number of conceptual and commercially available intravaginal veterinary drug delivery systems have been developed (Figure 15.4) for intravaginal administration of progesterone to cows with the aim of controlUng the estrous... 

Table 15.4 presents some of the intravaginal veterinary drug delivery systems for bovine estrus synchronization. These devices contain progesterone uniformly distributed throughout the silicone matrix. As mentioned before, the initial progesterone load is higher than hormone solubility in the matrix to meet the therapeutic requirements. 

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