Dronabinol , antiemetic properties

Droleptan " droperidol. dromostanolone propionate drostanolone. dronabinol [inn. usan] (NSC 134454 Deltanyne " Marinol ) is a constituent of marijuana. It is the (6aR,10aR)-(-)-trans-form of A -tetrahydrocannabinol. It is a cannabinoid receptor agonist and has euphoric, mild psychotropic (hallucinogenic) and ANTIEMETIC properties. 

Cannabinoids Marijuana derivatives, including dronabinol [droe NAB i nol] and nabilone, are effective against moderately emetogenic chemotherapy. However, they are seldom first-line antiemetics because of their serious side effects, including dysphoria, hallucinations, sedation, vertigo, and disorientation. In spite of their psychotropic properties (see p. 105), the antiemetic action of cannabinoids may not involve the brain synthetic cannabinoids having no psychotropic activity, nevertheless are antiemetic. 

Dronabinol is prescribed for its antiemetic and appetite stimulant properties. Marijuana is primarily a drug of abuse, although it is currently used by patients for the same purposes as dronabinol. 

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